A mechanism is provided for providing resource affinity for multi-queue network adapters via dynamic reconfiguration. A device driver allocates an initial queue pair within a memory. The device driver determines whether workload of the data processing system has risen above a predetermined high threshold. Responsive to the workload rising above the predetermined high threshold, the device driver allocates and initializes an additional queue pair in the memory. The device driver programs a receive side scaling (RSS) mechanism in a network adapter to allow for dynamic insertion of an additional processing engine associated with the additional queue pair. The device driver enables transmit tuple hashing to the additional queue pair.