Invention Grant
- Patent Title: Nanopore and carbon nanotube based DNA sequencer
- Patent Title (中): 纳米孔和基于碳纳米管的DNA测序仪
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Application No.: US12920817Application Date: 2009-03-18
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Publication No.: US08961757B2Publication Date: 2015-02-24
- Inventor: Colin Nuckolls , Jinyao Tang , Stuart Lindsay , Jin He , Peiming Zhang , Kevin Reinhart
- Applicant: Colin Nuckolls , Jinyao Tang , Stuart Lindsay , Jin He , Peiming Zhang , Kevin Reinhart
- Applicant Address: US AZ Scottsdale US NY New York
- Assignee: Arizona Board of Regents, a body corporate of the State of Arizona Acting for and on behalf of Arizona State University,The Trustees of Columbia University in the City of New York
- Current Assignee: Arizona Board of Regents, a body corporate of the State of Arizona Acting for and on behalf of Arizona State University,The Trustees of Columbia University in the City of New York
- Current Assignee Address: US AZ Scottsdale US NY New York
- Agency: Cooley LLP
- Agent Brian P. Hopkins; Dhruv Sud
- International Application: PCT/US2009/037563 WO 20090318
- International Announcement: WO2009/117517 WO 20090924
- Main IPC: G01N27/327
- IPC: G01N27/327 ; C12Q1/68 ; G01N33/487

Abstract:
The present invention provides a device for analyzing the composition of a heteropolymer comprising a carbon nanotube through which the heteropolymer is driven by electrophoresis. The carbon nanotube also serves as one electrode in a reading circuit. One end of the carbon nanotube is held in close proximity to a second electrode, and each end of the carbon nanotube is functionalized with flexibly-tethered chemical-recognition moieties, such that one will bind one site on the emerging polymer, and the second will bind another site in close proximity, generating an electrical signal between the two electrodes when the circuit is completed by the process of chemical recognition.
Public/Granted literature
- US20110168562A1 Nanopore and Carbon Nanotube Based DNA Sequencer Public/Granted day:2011-07-14
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