Invention Grant
US08961951B2 Baculoviruses with enhanced virion production and a method for the production of baculoviruses
有权
具有增强的病毒粒子生产的杆状病毒和产生杆状病毒的方法
- Patent Title: Baculoviruses with enhanced virion production and a method for the production of baculoviruses
- Patent Title (中): 具有增强的病毒粒子生产的杆状病毒和产生杆状病毒的方法
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Application No.: US12667956Application Date: 2008-07-03
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Publication No.: US08961951B2Publication Date: 2015-02-24
- Inventor: Gary Blissard , Jian Zhou
- Applicant: Gary Blissard , Jian Zhou
- Applicant Address: US NY Ithaca
- Assignee: Boyce Thompson Institute for Plant Research
- Current Assignee: Boyce Thompson Institute for Plant Research
- Current Assignee Address: US NY Ithaca
- Agency: Brown & Michaels, PC
- International Application: PCT/US2008/069132 WO 20080703
- International Announcement: WO2009/014878 WO 20090129
- Main IPC: A01N63/00
- IPC: A01N63/00 ; C12P21/06 ; C12N15/00 ; C12N15/09 ; C12N7/00 ; C07K14/005 ; C12N15/86
Abstract:
The present invention provides a method for restoring budding capability to GP64null baculoviruses including gp64null AcMNPV by expressing therein a portion of the VSV G protein gene or a truncated “stem” portion of the GP64 gene. Other embodiments provide methods to use portions of the G-stem or GP64 protein to target foreign proteins for display on virions.
Public/Granted literature
- US20100323398A1 Baculoviruses With Enhanced Virion Production and a Method for the Production of Baculoviruses Public/Granted day:2010-12-23
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