Invention Grant
US08961959B2 Glucosylceramide synthase inhibitors and therapeutic methods using the same
有权
葡萄糖神经酰胺合酶抑制剂及其治疗方法
- Patent Title: Glucosylceramide synthase inhibitors and therapeutic methods using the same
- Patent Title (中): 葡萄糖神经酰胺合酶抑制剂及其治疗方法
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Application No.: US13652016Application Date: 2012-10-15
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Publication No.: US08961959B2Publication Date: 2015-02-24
- Inventor: Scott Larsen , Akira Abe , Liming Shu , Michael William Wilson , Richard F. Keep , James A. Shayman
- Applicant: The Regents of the University of Michigan
- Applicant Address: US MI Ann Arbor
- Assignee: The Regents of the University of Michigan
- Current Assignee: The Regents of the University of Michigan
- Current Assignee Address: US MI Ann Arbor
- Agency: Marshall, Gerstein & Borun LLP
- Main IPC: A61K38/43
- IPC: A61K38/43 ; A01N43/36 ; A61K31/40 ; A61K48/00 ; A01N33/18 ; A01N33/24 ; A61K31/045 ; C07D405/00 ; C07D207/08 ; C07D207/46 ; C07D295/04 ; A61K45/06 ; C07D319/18 ; C07D295/125 ; C07D295/135
Abstract:
Glucosylceramide synthase inhibitors and compositions containing the same are disclosed. Methods of using the glucosylceramide synthase inhibitors in the treatment of diseases and conditions wherein inhibition of glucosylceramide synthase provides a benefit, like Gaucher disease and Fabry disease, also are disclosed.
Public/Granted literature
- US20130095089A1 GLUCOSYLCERAMIDE SYNTHASE INHIBITORS AND THERAPEUTIC METHODS USING THE SAME Public/Granted day:2013-04-18
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