Invention Grant
- Patent Title: Antibodies against ERBB3 and uses thereof
- Patent Title (中): 针对ERBB3的抗体及其用途
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Application No.: US12904492Application Date: 2010-10-14
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Publication No.: US08961966B2Publication Date: 2015-02-24
- Inventor: Birgit Schoeberl , Ulrik Nielsen , Michael Feldhaus , Arumugam Muruganandam , David Buckler
- Applicant: Birgit Schoeberl , Ulrik Nielsen , Michael Feldhaus , Arumugam Muruganandam , David Buckler
- Applicant Address: US MA Cambridge
- Assignee: Merrimack Pharmaceuticals, Inc.
- Current Assignee: Merrimack Pharmaceuticals, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Nelson Mullins Riley & Scarborough LLP
- Agent Jane E. Remillard, Esq.; Jill Gorny Sloper, Esq.
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07K16/00 ; C07K16/28 ; C07K16/32 ; A61K31/337 ; A61K31/517 ; A61K33/24 ; A61K39/00
Abstract:
The present invention provides a novel class of monoclonal antibodies which bind ErbB3 receptor and inhibits various ErbB3 functions. For example, the antibodies described herein are capable of binding to ErbB3 and inhibiting EGF-like ligand mediated phosphorylation of the receptor.
Public/Granted literature
- US20110123523A1 ANTIBODIES AGAINST ERBB3 AND USES THEREOF Public/Granted day:2011-05-26
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