Invention Grant
- Patent Title: Method for purifying the rabies virus
- Patent Title (中): 纯化狂犬病病毒的方法
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Application No.: US12756590Application Date: 2010-04-08
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Publication No.: US08961997B2Publication Date: 2015-02-24
- Inventor: Virginie Fabre , Céline Rocca , Pierre Riffard , Eric Calvosa
- Applicant: Virginie Fabre , Céline Rocca , Pierre Riffard , Eric Calvosa
- Applicant Address: FR Lyons
- Assignee: Sanofi Pasteur SA
- Current Assignee: Sanofi Pasteur SA
- Current Assignee Address: FR Lyons
- Agency: McDonnell Boehnen Hulbert & Berghoff LLP
- Priority: FR0952310 20090408
- Main IPC: B01D15/08
- IPC: B01D15/08 ; B01D15/00 ; C02F1/42 ; A61K39/205 ; C12N7/00 ; A61K39/12
Abstract:
The subject of the invention is a method for purifying the rabies virus, comprising a single ion-exchange chromatography step, said step being cation exchange chromatography according to which: a) the supernatant of a culture of cells infected with this virus is brought into contact with a cation exchange chromatography support comprising a polymethacrylate matrix onto which sulfoisobutyl groups have been grafted such that the rabies virus binds to this support, and; b) the virus is eluted from its support.
Public/Granted literature
- US20100260798A1 Method for purifying the rabies virus Public/Granted day:2010-10-14
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