Invention Grant
- Patent Title: Quinoxalinyl derivatives
- Patent Title (中): 喹喔啉衍生物
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Application No.: US12327538Application Date: 2008-12-03
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Publication No.: US08962551B2Publication Date: 2015-02-24
- Inventor: Deqiang Niu , Dong Liu , Joel D. Moore , Guoyou Xu , Ying Sun , Yonghua Gai , Datong Tang , Yat Sun Or , Zhe Wang
- Applicant: Deqiang Niu , Dong Liu , Joel D. Moore , Guoyou Xu , Ying Sun , Yonghua Gai , Datong Tang , Yat Sun Or , Zhe Wang
- Applicant Address: US MA Watertown
- Assignee: Enanta Pharmaceuticals, Inc.
- Current Assignee: Enanta Pharmaceuticals, Inc.
- Current Assignee Address: US MA Watertown
- Agency: Locke Lord LLP
- Agent Jeffrey D. Hsi; Stephen W. Rafferty
- Main IPC: A61K38/00
- IPC: A61K38/00 ; A01N37/18 ; C07D487/04 ; A61K38/21 ; C07K5/078 ; C07K5/087
Abstract:
The present invention relates to compounds of Formula I or II, or pharmaceutically acceptable salts, esters, or prodrugs thereof: which inhibit serine protease activity, particularly the activity of hepatitis C virus (HCV) NS3-NS4A protease. Consequently, the compounds of the present invention interfere with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a subject by administering a pharmaceutical composition comprising a compound of the present invention.
Public/Granted literature
- US20090180981A1 QUINOXALINYL DERIVATIVES Public/Granted day:2009-07-16
Information query
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