Invention Grant
US08962608B2 Cycloalkylnitrile pyrazole carboxamides as janus kinase inhibitors
有权
环烷基腈吡唑甲酰胺作为甘蔗激酶抑制剂
- Patent Title: Cycloalkylnitrile pyrazole carboxamides as janus kinase inhibitors
- Patent Title (中): 环烷基腈吡唑甲酰胺作为甘蔗激酶抑制剂
-
Application No.: US14345976Application Date: 2012-09-21
-
Publication No.: US08962608B2Publication Date: 2015-02-24
- Inventor: Jason Brubaker , Christopher Dinsmore , Dawn Marie Hoffman , Joon Jung , Duan Liu , Scott Peterson , Tony Siu , Luis E. Torres , Hongjun Zhang , Zhongyong Wei , Feng Shi
- Applicant: Jason Brubaker , Christopher Dinsmore , Dawn Marie Hoffman , Joon Jung , Duan Liu , Scott Peterson , Tony Siu , Luis E. Torres , Hongjun Zhang , Zhongyong Wei , Feng Shi
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Patricia A. Shatynski; Laura Ginkel
- International Application: PCT/CN2012/001291 WO 20120921
- International Announcement: WO2013/040863 WO 20130328
- Main IPC: A61K31/397
- IPC: A61K31/397 ; A61K31/5377 ; A61K31/501 ; A61K31/497 ; A61K31/415 ; C07D231/38 ; C07D403/08 ; C07D403/12 ; C07D405/08 ; C07D401/12 ; C07D401/14 ; C07D405/12 ; C07D409/12 ; C07D413/12 ; C07D401/04 ; C07D403/04 ; C07D405/04 ; C07D401/06 ; C07D403/06 ; C07D405/06 ; C07D405/14 ; C07D409/04 ; C07D413/14 ; C07D417/14
Abstract:
The instant invention provides compounds of formula I which are JAK inhibitors, and as such are useful for the treatment of JAK-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer.
Public/Granted literature
- US20140243309A1 CYCLOALKYLNITRILE PYRAZOLE CARBOXAMIDES AS JANUS KINASE INHIBITORS Public/Granted day:2014-08-28
Information query
