Invention Grant
US08962810B2 Macrocyclic heterocyclic compound for inhibiting hepatitis C virus and preparation and use thereof
有权
用于抑制丙型肝炎病毒的大环杂环化合物及其制备和用途
- Patent Title: Macrocyclic heterocyclic compound for inhibiting hepatitis C virus and preparation and use thereof
- Patent Title (中): 用于抑制丙型肝炎病毒的大环杂环化合物及其制备和用途
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Application No.: US14126554Application Date: 2012-06-14
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Publication No.: US08962810B2Publication Date: 2015-02-24
- Inventor: Zheng-yun James Zhan
- Applicant: Zheng-yun James Zhan
- Applicant Address: CN Shanghai
- Assignee: AB Pharma Ltd.
- Current Assignee: AB Pharma Ltd.
- Current Assignee Address: CN Shanghai
- Agency: Greenberg Traurig, LLP
- Agent Fang Xie
- Priority: CN201110162701 20110616
- International Application: PCT/CN2012/000821 WO 20120614
- International Announcement: WO2012/171332 WO 20121220
- Main IPC: A61K38/00
- IPC: A61K38/00 ; C07K16/00 ; C07D498/20 ; C07K5/083 ; C07K5/062 ; A61K31/407 ; A61K45/06 ; C07D498/16 ; C07D498/22
Abstract:
The present invention discloses a class of novel macro-heterocyclic compounds represented by the formula Ia or Ib, and their intermediates, preparation methods and the uses. The macro-heterocyclic compounds of the present invention have good inhibitory activities against hepatitis C virus (HCV), and can be used to treat HCV infection effectively by its excellent inhibition against HCV, low toxicity and side effects.
Public/Granted literature
- US20140205567A1 Macrocyclic Heterocyclic Compound for Inhibiting Hepatitis C Virus and Preparation and Use Thereof Public/Granted day:2014-07-24
Information query
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