Invention Grant
- Patent Title: Interleukin-1α antibodies and methods of use
- Patent Title (中): 白细胞介素-1α抗体及其使用方法
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Application No.: US13225029Application Date: 2011-09-02
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Publication No.: US08962814B2Publication Date: 2015-02-24
- Inventor: John Simard
- Applicant: John Simard
- Applicant Address: CA Vancouver
- Assignee: XBiotech, Inc.
- Current Assignee: XBiotech, Inc.
- Current Assignee Address: CA Vancouver
- Agent Stanley A. Kim
- Main IPC: C07K1/22
- IPC: C07K1/22 ; C07K16/24 ; C12N5/071 ; C12N5/09 ; G01N33/68 ; C07K1/14 ; C07K1/16 ; G01N33/537 ; A61K39/00
Abstract:
Fully human monoclonal Abs includes (i) an antigen-binding variable region that exhibits very high binding affinity for IL-1α and (ii) a constant region that is effective at both activating the complement system though C1q binding and binding to several different Fc receptors.
Public/Granted literature
- US20120015384A1 Interleukin-1 Alpha Antibodies and Methods of Use Public/Granted day:2012-01-19
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