Invention Grant
- Patent Title: 2-pyridone antimicrobial compositions
- Patent Title (中): 2-吡啶酮抗微生物组合物
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Application No.: US13821250Application Date: 2011-09-16
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Publication No.: US08962842B2Publication Date: 2015-02-24
- Inventor: Patrick Roussel , Jutta Heim , Peter Schneider , Christian Bartels , Yaoquan Liu , Glen Dale , Daniel Milligan
- Applicant: Patrick Roussel , Jutta Heim , Peter Schneider , Christian Bartels , Yaoquan Liu , Glen Dale , Daniel Milligan
- Applicant Address: CH Reinach
- Assignee: Evolva SA
- Current Assignee: Evolva SA
- Current Assignee Address: CH Reinach
- Agency: McDonnell Boehnen Hulbert & Berghoff LLP
- International Application: PCT/US2011/052003 WO 20110916
- International Announcement: WO2012/047487 WO 20120412
- Main IPC: C07D455/02
- IPC: C07D455/02 ; A61K31/4375
Abstract:
Described are a series of 2-pyridone compounds as a potent and selective new class of type II topoisomerase inhibitors with broad-spectrum antimicrobial activity having the general formula (I); where R1, R2, X, and Y are defined herein Such compounds can be used in methods for treating an infection caused by a gram-positive pathogen, a gram-negative pathogen, or a drug-resistant strains thereof.
Public/Granted literature
- US20130245035A1 2-PYRIDONE ANTIMICROBIAL COMPOSITIONS Public/Granted day:2013-09-19
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