Latch-up of CMOS devices is improved by using a structure having electrically coupled but floating doped regions between the N-channel and P-channel devices. The doped regions desirably lie substantially parallel to the source-drain regions of the devices between the Pwell and Nwell regions in which the source-drain regions are located. A first (“N BAR”) doped region forms a PN junction with the Pwell, spaced apart from a source/drain region in the Pwell, and a second (“P BAR”) doped region forms a PN junction with the Nwell, spaced apart from a source/drain region in the Nwell. A further NP junction lies between the N BAR and P BAR regions. The N BAR and P BAR regions are ohmically coupled, preferably by a low resistance metal conductor, and otherwise floating with respect to the device or circuit reference potentials (e.g., Vss, Vdd).