Invention Grant
US08968540B2 Trans-base tunnel reader for sequencing 有权
用于排序的Trans-base隧道读取器

Trans-base tunnel reader for sequencing
Abstract:
A device for reading the sequence of a polymer, consisting of a first electrode and a second electrode, each electrode being functionalized with a reader molecule strongly bonded to the electrodes, but forming weak bonds with a molecule to be sequenced. In particular, the reader molecule is designed to form bonds with at least two points on the target molecule such that the target molecule is trapped between a first reader molecule on one electrode and a second reader molecule on the second electrode, with the overall size of the molecular complex being small enough to permit significant electric current to flow.
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