Invention Grant
- Patent Title: Trans-base tunnel reader for sequencing
- Patent Title (中): 用于排序的Trans-base隧道读取器
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Application No.: US13122104Application Date: 2009-10-06
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Publication No.: US08968540B2Publication Date: 2015-03-03
- Inventor: Kevin Reinhart , Stuart Lindsay , Peiming Zhang
- Applicant: Kevin Reinhart , Stuart Lindsay , Peiming Zhang
- Applicant Address: US AZ Scottsdale
- Assignee: Arizona Board of Regents, a Body Corporate of the State of Arizona Acting for and on Behalf of Arizona State University
- Current Assignee: Arizona Board of Regents, a Body Corporate of the State of Arizona Acting for and on Behalf of Arizona State University
- Current Assignee Address: US AZ Scottsdale
- Agency: Cooley LLP
- Priority: WOPCT/US09/037563 20090318; WOPCT/US09/037570 20090318
- International Application: PCT/US2009/059693 WO 20091006
- International Announcement: WO2010/042514 WO 20100415
- Main IPC: G01N27/447
- IPC: G01N27/447 ; G01N27/453 ; G01N27/327 ; C12Q1/68 ; G01N33/487

Abstract:
A device for reading the sequence of a polymer, consisting of a first electrode and a second electrode, each electrode being functionalized with a reader molecule strongly bonded to the electrodes, but forming weak bonds with a molecule to be sequenced. In particular, the reader molecule is designed to form bonds with at least two points on the target molecule such that the target molecule is trapped between a first reader molecule on one electrode and a second reader molecule on the second electrode, with the overall size of the molecular complex being small enough to permit significant electric current to flow.
Public/Granted literature
- US20130186757A1 Nanopore and Carbon Nanotube Based Dna Sequencer and A Serial Recognition Elements Public/Granted day:2013-07-25
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