Invention Grant
- Patent Title: Heat shock protein GP96 vaccination and methods of using same
- Patent Title (中): 热休克蛋白GP96疫苗接种及使用方法
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Application No.: US12933567Application Date: 2009-03-19
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Publication No.: US08968720B2Publication Date: 2015-03-03
- Inventor: Eckhard R. Podack , Joseph R. Rosenblatt
- Applicant: Eckhard R. Podack , Joseph R. Rosenblatt
- Applicant Address: US FL Miami
- Assignee: University of Miami
- Current Assignee: University of Miami
- Current Assignee Address: US FL Miami
- Agency: Fish & Richardson P.C.
- International Application: PCT/US2009/001727 WO 20090319
- International Announcement: WO2009/117116 WO 20090924
- Main IPC: A01N63/00
- IPC: A01N63/00 ; A61K39/395 ; C12N15/63 ; A61K38/17 ; A61K39/00 ; C07K16/28 ; C12N5/16 ; A61K35/12
Abstract:
The invention provides a tumor cell genetically modified to express a nucleic acid encoding a secreted form of a heat shock protein (hsp) gp96 polypeptide. The invention also provides a method of stimulating an immune response to a tumor by administering a tumor cell genetically modified to express a nucleic acid encoding a secreted form of a gp96 polypeptide.
Public/Granted literature
- US20110171211A1 HEAT SHOCK PROTEIN GP96 VACCINATION AND METHODS OF USING SAME Public/Granted day:2011-07-14
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