Invention Grant
- Patent Title: Controlled release coat-core tablet
- Patent Title (中): 控释外套芯片
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Application No.: US13704345Application Date: 2011-06-15
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Publication No.: US08968779B2Publication Date: 2015-03-03
- Inventor: Kentaro Fujinaga , Susumu Maruo , Hideaki Nakamura , Kenji Sunagawa , Tsutomu Mochizuki , Michiharu Kageyama
- Applicant: Kentaro Fujinaga , Susumu Maruo , Hideaki Nakamura , Kenji Sunagawa , Tsutomu Mochizuki , Michiharu Kageyama
- Applicant Address: JP Tokyo
- Assignee: Teijin Pharma Limited
- Current Assignee: Teijin Pharma Limited
- Current Assignee Address: JP Tokyo
- Agency: Sughrue Mion, PLLC
- Priority: JP2010-137322 20100616; JP2010-137323 20100616
- International Application: PCT/JP2011/063713 WO 20110615
- International Announcement: WO2011/158870 WO 20111222
- Main IPC: A61K9/24
- IPC: A61K9/24 ; A61K9/28 ; A61K31/426 ; A61K9/20

Abstract:
Disclosed is a controlled release nucleated tablet which is composed of an inner nucleus and an outer layer that covers the inner nucleus and is capable of maintaining the level of 2-(3-cyano-4-isobutyloxyphenyl)-4-methyl-5-thiazolecarboxylic acid in the blood to a certain value or higher for a long period of time. The controlled release nucleated tablet is characterized in that the inner nucleus contains 2-(3-cyano-4-isobutyloxyphenyl)-4-methyl-5-thiazolecarboxylic acid and the outer layer contains 2-(3-cyano-4-isobutyloxyphenyl)-4-methyl-5-thiazolecarboxylic acid and a gel-forming water-soluble polymer that is in an amount of 16 (w/w) % or more relative to the weight of the outer layer.
Public/Granted literature
- US20130089609A1 CONTROLLED RELEASE NUCLEATED TABLET Public/Granted day:2013-04-11
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