Invention Grant
- Patent Title: Materials and methods for predicting recurrence of non-small cell lung cancer
- Patent Title (中): 预测非小细胞肺癌复发的材料和方法
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Application No.: US12721742Application Date: 2010-03-11
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Publication No.: US08969001B2Publication Date: 2015-03-03
- Inventor: Lela Buckingham
- Applicant: Lela Buckingham
- Applicant Address: US IL Chicago
- Assignee: Rush University Medical Center
- Current Assignee: Rush University Medical Center
- Current Assignee Address: US IL Chicago
- Agency: McDermott Will & Emery LLP
- Main IPC: C12Q1/68
- IPC: C12Q1/68
Abstract:
Disclosed herein is a DNA methylation-based test for determining the recurrence or non-recurrence of a lung cancer such as NSCLC after treatment. The assays involve the detection of methylation of the BAX gene promoter alone or in combination with other genes. The test is suitable for monitoring treatment of subjects with lung cancer for which methylation differs by stage of the disease and by treatment regimen.
Public/Granted literature
- US20100233707A1 MATERIALS AND METHODS FOR PREDICTING RECURRENCE OF NON-SMALL CELL LUNG CANCER Public/Granted day:2010-09-16
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