Invention Grant
- Patent Title: Methods and kits for diagnosing Sjögren's syndrome
- Patent Title (中): 诊断Sjögren综合征的方法和试剂盒
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Application No.: US14078020Application Date: 2013-11-12
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Publication No.: US08969015B2Publication Date: 2015-03-03
- Inventor: Denise L. Faustman
- Applicant: The General Hospital Corporation
- Applicant Address: US MA Boston
- Assignee: The General Hospital Corporation
- Current Assignee: The General Hospital Corporation
- Current Assignee Address: US MA Boston
- Agency: Clark & Elbing LLP
- Agent Paul T. Clark, Esq.; Todd Armstrong
- Main IPC: G01N33/53
- IPC: G01N33/53 ; G01N33/564
Abstract:
The invention features methods and kits for determining the presence of, or a predisposition to develop, Sjögren's syndrome in humans. The invention features methods to detect changes in the levels of one or more LMP-2 protein isoforms, in particular phosphorylated isoforms of LMP-2, and to detect changes in cellular protein phosphorylation and ubiquitination in samples from Sjögren's patients.
Public/Granted literature
- US20140134644A1 METHODS AND KITS FOR DIAGNOSING SJOGREN'S SYNDROME Public/Granted day:2014-05-15
Information query
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