Invention Grant
- Patent Title: Neuronal specific targeting of caveolin expression to restore synaptic signaling and improve cognitive function in the neurodegenerative brain and motor function in spinal cord
- Patent Title (中): 神经元特异性靶向窖蛋白表达恢复突触信号并改善脊髓神经退行性脑和运动功能的认知功能
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Application No.: US13883503Application Date: 2011-11-07
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Publication No.: US08969077B2Publication Date: 2015-03-03
- Inventor: Brian P. Head , Piyush M. Patel , Hemal Patel , David M. Roth
- Applicant: Brian P. Head , Piyush M. Patel , Hemal Patel , David M. Roth
- Applicant Address: US CA Oakland
- Assignee: The Regents of the University of California
- Current Assignee: The Regents of the University of California
- Current Assignee Address: US CA Oakland
- Agency: Adriano & Associates
- International Application: PCT/US2011/059635 WO 20111107
- International Announcement: WO2012/061828 WO 20120510
- Main IPC: A61K48/00
- IPC: A61K48/00 ; A61K31/7088 ; A61K38/17 ; C12N15/86
Abstract:
The invention provides an expression system for producing Caveolin-1 in neuronal cells or neural stem cells comprising a neuron-specific regulatory element and a nucleic acid sequence encoding Caveolin-1.
Public/Granted literature
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