Invention Grant
- Patent Title: Tocotrienol esters
- Patent Title (中): 生育三烯酚酯
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Application No.: US13021361Application Date: 2011-02-04
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Publication No.: US08969303B2Publication Date: 2015-03-03
- Inventor: Khalid A. El Sayed , Paul W. Sylvester
- Applicant: Khalid A. El Sayed , Paul W. Sylvester
- Applicant Address: CN Hong Kong
- Assignee: First Tech International Limited
- Current Assignee: First Tech International Limited
- Current Assignee Address: CN Hong Kong
- Agency: Edel Patents LLC
- Agent John B. Edel
- Main IPC: A01N43/16
- IPC: A01N43/16 ; A61K31/355 ; A61K38/00 ; A61P35/00 ; C07D311/72 ; A61K31/19 ; A61K31/192
Abstract:
Esters of tocotrienols having pharmacological activities pertinent to the treatment of breast cancer and other forms of cancer are disclosed herein. Among those compounds is (Z)-4-oxo-4-((R)-2,5,7,8-tetramethyl-2-((3E,7E)-4,8,12-trimethyltrideca-3,7,11-trienyl)chroman-6-yloxy)but-2-enoic acid. Tocotrienol esters were used to inhibit the growth and migration of +SA mammary epithelial cells and highly metastatic human breast cancer MDA-MB-231 cells respectively.
Public/Granted literature
- US20110196030A1 TOCOTRIENOL ESTERS Public/Granted day:2011-08-11
Information query
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