Invention Grant
- Patent Title: MicroRNA compounds and methods for modulating miR-21 activity
- Patent Title (中): 微RNA化合物和调节miR-21活性的方法
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Application No.: US13869177Application Date: 2013-04-24
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Publication No.: US08969317B2Publication Date: 2015-03-03
- Inventor: Balkrishen Bhat , Eric Marcusson
- Applicant: Regulus Therapeutics Inc.
- Applicant Address: US CA San Diego
- Assignee: Regulus Therapeutics Inc.
- Current Assignee: Regulus Therapeutics Inc.
- Current Assignee Address: US CA San Diego
- Agency: Casimir Jones, S.C.
- Main IPC: C12N15/11
- IPC: C12N15/11 ; C07H21/02 ; C12N15/113 ; A61K31/712 ; A61K45/06
Abstract:
Described herein are compositions and methods for the inhibition of miR-21 activity. The compositions have certain nucleoside modification patterns that yield potent inhibitors of miR-21 activity. The compositions may be used to inhibit miR-21, and also to treat diseases associated with abnormal expression of miR-21, such as fibrosis and cancer.
Public/Granted literature
- US20130289093A1 MICRORNA COMPOUNDS AND METHODS FOR MODULATING MIR-21 ACTIVITY Public/Granted day:2013-10-31
Information query
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