Invention Grant
- Patent Title: Bispecific aptamers mediating tumour cell lysis
- Patent Title (中): 介导肿瘤细胞裂解的双特异性适体
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Application No.: US13992608Application Date: 2011-12-12
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Publication No.: US08969318B2Publication Date: 2015-03-03
- Inventor: Lars Toleikis , Ralf Guenther , Bjoern Hock , Achim Doerner
- Applicant: Lars Toleikis , Ralf Guenther , Bjoern Hock , Achim Doerner
- Applicant Address: DE Darmstadt
- Assignee: Merck Patent GmbH
- Current Assignee: Merck Patent GmbH
- Current Assignee Address: DE Darmstadt
- Agency: Millen, White, Zelano, Branigan, P.C.
- Priority: EP10015522 20101210
- International Application: PCT/EP2011/006254 WO 20111212
- International Announcement: WO2012/076190 WO 20120614
- Main IPC: A61K48/00
- IPC: A61K48/00 ; C07H21/02 ; C07H21/04 ; C12Q1/68
Abstract:
Disclosed are bispecific aptamers binding with high specifity to a tumour specific antigen (TSA) and a effector cell specific antigen (ESA) for treatment of cancer.
Public/Granted literature
- US20140039042A1 BISPECIFIC APTAMERS MEDIATING TUMOUR CELL LYSIS Public/Granted day:2014-02-06
Information query
