Invention Grant
- Patent Title: Benzonitrile derivatives as kinase inhibitors
- Patent Title (中): 苄腈衍生物作为激酶抑制剂
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Application No.: US14342911Application Date: 2012-08-13
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Publication No.: US08969335B2Publication Date: 2015-03-03
- Inventor: Guenter Hoelzemann , Dieter Dorsch , Hans-Michael Eggenweiler
- Applicant: Guenter Hoelzemann , Dieter Dorsch , Hans-Michael Eggenweiler
- Applicant Address: DE Darmstadt
- Assignee: MERCK PATENT GmbH
- Current Assignee: MERCK PATENT GmbH
- Current Assignee Address: DE Darmstadt
- Agency: Millen, White, Zelano & Branigan, P.C.
- Priority: DE102011112978 20110909
- International Application: PCT/EP2012/003449 WO 20120813
- International Announcement: WO2013/034238 WO 20130314
- Main IPC: A61K31/506
- IPC: A61K31/506 ; A61K31/4523 ; A61K31/4427 ; C07D401/04 ; C07D401/12 ; C07D401/14 ; C07D403/04 ; C07D403/12 ; C07D403/14 ; C07D405/14 ; C07D413/14 ; C07D417/14 ; C07D471/04 ; C07D491/10 ; A61K31/4439 ; A61K31/444 ; A61K31/4545 ; A61K31/497 ; A61K31/501 ; A61K31/5377 ; A61K45/06 ; C07D491/107
Abstract:
Compounds of the formula I, in which R1, R2, X and Y have the meanings indicated in Claim 1, are inhibitors of TBK1 and IKKε and can be employed, inter alia, for the treatment of cancer and inflammatory diseases.
Public/Granted literature
- US20140228340A1 BENZONITRILE DERIVATIVES AS KINASE INHIBITORS Public/Granted day:2014-08-14
Information query
IPC分类:
