Invention Grant
- Patent Title: Histone demethylase inhibitors
- Patent Title (中): 组蛋白脱甲基酶抑制剂
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Application No.: US14134989Application Date: 2013-12-19
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Publication No.: US08969343B2Publication Date: 2015-03-03
- Inventor: Toufike Kanouni , Jeffrey Alan Stafford , James Marvin Veal , Michael Brennen Wallace
- Applicant: Quanticel Pharmaceuticals, Inc.
- Applicant Address: US CA San Diego
- Assignee: Quanticel Pharmaceuticals, Inc.
- Current Assignee: Quanticel Pharmaceuticals, Inc.
- Current Assignee Address: US CA San Diego
- Agency: Wilson Sonsini Goodrich & Rosati
- Main IPC: A61K31/535
- IPC: A61K31/535 ; C07D401/00 ; C07D405/00 ; C07D401/12 ; C07D401/14 ; C07D403/12 ; C07D405/14 ; C07D413/12 ; C07D471/04

Abstract:
The present invention relates generally to compositions and methods for treating cancer and neoplastic disease. Provided herein are substituted 3-aminopyridine derivative compounds, substituted 3-aminopyridazine derivative compounds, and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for inhibition histone demethylase. Furthermore, the subject compounds and compositions are useful for the treatment of cancer, such as prostate cancer, breast cancer, bladder cancer, lung cancer and/or melanoma and the like.
Public/Granted literature
- US20140171432A1 HISTONE DEMETHYLASE INHIBITORS Public/Granted day:2014-06-19
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