Invention Grant
- Patent Title: Dibenzooxepin derivative
- Patent Title (中): 二苯氧基苯酚衍生物
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Application No.: US14236545Application Date: 2012-08-03
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Publication No.: US08969345B2Publication Date: 2015-03-03
- Inventor: Keisuke Yamamoto , Tomohiro Tamura , Rina Nakamura , Kimihisa Ueno , Shintaro Hosoe
- Applicant: Keisuke Yamamoto , Tomohiro Tamura , Rina Nakamura , Kimihisa Ueno , Shintaro Hosoe
- Applicant Address: JP Tokyo
- Assignee: Kyowa Hakko Kirin Co., Ltd.
- Current Assignee: Kyowa Hakko Kirin Co., Ltd.
- Current Assignee Address: JP Tokyo
- Agency: Leydig, Voit & Mayer, Ltd.
- Priority: JP2011-169701 20110803
- International Application: PCT/JP2012/069876 WO 20120803
- International Announcement: WO2013/018899 WO 20130207
- Main IPC: C07D413/14
- IPC: C07D413/14 ; C07D471/04 ; C07D487/04 ; C07D495/04 ; A61K31/4245 ; A61K31/437 ; A61K31/4439 ; A61K31/454 ; A61K31/4985 ; A61K31/5025 ; A61K31/519
Abstract:
A dibenzoxepin derivative represented by the following general formula (I) wherein Y is a hydrogen atom and the like, RA is a hydrogen atom and the like, X is the formula (b3) wherein RB is a hydrogen atom and the like, and the like, A is the formula (a18) wherein R1 is a hydrogen atom and the like, and RC and RD are the same or different and each is a hydrogen atom and the like, and the like, which has a PPARγ agonist activity and the like, and useful as a therapeutic agent and/or prophylaxis agent and the like for type 2 diabetes and the like, or a pharmaceutically acceptable salt thereof and the like is provided.
Public/Granted literature
- US20140163008A1 DIBENZOOXEPIN DERIVATIVE Public/Granted day:2014-06-12
Information query
