Invention Grant
US08969355B2 1-[2-(2,4 dimethylphenylsulfanyl)-phenyl]piperazine as a compound with combined serotonin reuptake, 5-HT3 and 5-HT1a activity for the treatment of cognitive impairment
有权
1- [2-(2,4-二甲基苯基硫烷基) - 苯基]哌嗪作为具有组合的5-羟色胺再摄取的化合物,用于治疗认知障碍的5-HT3和5-HT1a活性
- Patent Title: 1-[2-(2,4 dimethylphenylsulfanyl)-phenyl]piperazine as a compound with combined serotonin reuptake, 5-HT3 and 5-HT1a activity for the treatment of cognitive impairment
- Patent Title (中): 1- [2-(2,4-二甲基苯基硫烷基) - 苯基]哌嗪作为具有组合的5-羟色胺再摄取的化合物,用于治疗认知障碍的5-HT3和5-HT1a活性
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Application No.: US14480949Application Date: 2014-09-09
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Publication No.: US08969355B2Publication Date: 2015-03-03
- Inventor: Benny Bang-Andersen , Andre Faldt , Rene Holm , Heidi Lopez de Diego
- Applicant: H. Lundbeck A/S
- Applicant Address: DK Valby
- Assignee: H. Lundbeck A/S
- Current Assignee: H. Lundbeck A/S
- Current Assignee Address: DK Valby
- Agency: Fish & Richardson P.C.
- Priority: DK200600824 20060616; DK200601223 20060922; DK200601384 20061025; DK200700427 20070320
- Main IPC: A61K31/495
- IPC: A61K31/495 ; C07D295/096 ; A61K9/14
![1-[2-(2,4 dimethylphenylsulfanyl)-phenyl]piperazine as a compound with combined serotonin reuptake, 5-HT3 and 5-HT1a activity for the treatment of cognitive impairment](/abs-image/US/2015/03/03/US08969355B2/abs.jpg.150x150.jpg)
Abstract:
This disclosure relates to a method of treating a disease selected from the group consisting of affective disorders, depression, major depressive disorder, anxiety, general anxiety disorder, social anxiety disorder, obsessive compulsive disorder, panic disorder, and panic attacks. The method includes administering a therapeutically effective amount of Compound I or a pharmaceutically acceptable salt thereof to a patient in need thereof, in which Compound I is 1-[2-(2,4-dimethylphenylsulfanyl)-phenyl]piperazine.
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