Invention Grant
- Patent Title: Gyrase and topoisomerase IV inhibitors
- Patent Title (中): 促旋酶和拓扑异构酶IV抑制剂
-
Application No.: US13908593Application Date: 2013-06-03
-
Publication No.: US08969359B2Publication Date: 2015-03-03
- Inventor: Arnaud Le Tiran , Anne-Laure Grillot , Paul S. Charifson , Youssef Laafiret Bennani , Hardwin O'Dowd , Emanuele Perola
- Applicant: Vertex Pharmaceuticals Incorporated
- Applicant Address: US MA Boston
- Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee Address: US MA Boston
- Agency: Brinks Gilson & Lione
- Main IPC: A01N43/54
- IPC: A01N43/54 ; C07D239/42 ; C07D401/04 ; C07D405/14 ; C07F9/6558
Abstract:
The present invention relates to a compound of formula (I) or a pharmaceutically acceptable salt thereof wherein X and R are as defined herein. The compounds of formula (I) are useful as gyrase and/or topoisomerase IV inhibitors for treating bacterial infections. The compounds of formula (I) either possess a broad range of anti-bacterial activity and advantageous toxicological properties or are prodrugs of compounds having said activity.
Public/Granted literature
- US20130289002A1 GYRASE AND TOPOISOMERASE IV INHIBITORS Public/Granted day:2013-10-31
Information query
IPC分类:
