Invention Grant
US08969366B2 Substituted pyrimidinylpyrrolopyridinone derivatives, process for their preparation and their use as kinase inhibitors
有权
取代的嘧啶基吡咯并吡喃酮衍生物，其制备方法及其作为激酶抑制剂的用途
- Patent Title: Substituted pyrimidinylpyrrolopyridinone derivatives, process for their preparation and their use as kinase inhibitors
- Patent Title (中): 取代的嘧啶基吡咯并吡喃酮衍生物，其制备方法及其作为激酶抑制剂的用途
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Application No.: US14010734Application Date: 2013-08-27
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Publication No.: US08969366B2Publication Date: 2015-03-03
- Inventor: Chiara Marchionni , Fabio Zuccotto , Alessandra Badari , Mauro Angiolini , Davide Carenzi , Marina Caldarelli , Maurizio Pulici
- Applicant: Chiara Marchionni , Fabio Zuccotto , Alessandra Badari , Mauro Angiolini , Davide Carenzi , Marina Caldarelli , Maurizio Pulici
- Applicant Address: IT Nerviano (MI)
- Assignee: Nerviano Medical Sciences S.R.L.
- Current Assignee: Nerviano Medical Sciences S.R.L.
- Current Assignee Address: IT Nerviano (MI)
- Agency: Scully, Scott, Murphy & Presser, P.C.
- Priority: EP09162719 20090615
- Main IPC: A01N43/54
- IPC: A01N43/54 ; A61K31/505 ; C07D471/04 ; A61K31/506 ; A61K45/06 ; A61N5/00
Abstract:
Pyrimidinylpyrrolopyridinone derivatives of formula (I) as defined in the specification, and pharmaceutically acceptable salts thereof, process for their preparation and pharmaceutical compositions comprising them are disclosed; the compounds of the invention may be useful, in therapy, in the treatment of diseases associated with a disregulated protein kinase activity, like cancer.
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