Invention Grant
- Patent Title: Abuse-resistant controlled-release opioid dosage form
- Patent Title (中): 滥用耐药阿片类药物剂型
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Application No.: US14136443Application Date: 2013-12-20
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Publication No.: US08969369B2Publication Date: 2015-03-03
- Inventor: Frank S. Caruso , Huai-Hung Kao
- Applicant: Purdue Pharma L.P.
- Applicant Address: US CT Stamford
- Assignee: Purdue Pharma L.P.
- Current Assignee: Purdue Pharma L.P.
- Current Assignee Address: US CT Stamford
- Agency: Dechert LLP
- Main IPC: A61K31/44
- IPC: A61K31/44 ; A61K9/48 ; A61K9/52 ; A61K9/22 ; A61K9/20 ; A61K31/485 ; A61K9/00

Abstract:
Abuse-resistant, controlled release opioid tablets are a combination containing an opioid antagonist such as naloxone at a level above that needed to suppress the euphoric effect of the opioid, if the combination were crushed to break the controlled release properties causing the opioid and opioid antagonist to be released as a immediate release product as a single dose. The controlled release nature of the table prevents the accumulation of orally effective amounts of opioid antagonist when taken normally. The opioid antagonist is contained in a controlled-release matrix and released, over time, with the opioid.
Public/Granted literature
- US20140107146A1 ABUSE-RESISTANT CONTROLLED-RELEASE OPIOID DOSAGE FORM Public/Granted day:2014-04-17
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