Invention Grant
US08969376B2 Pyrazolopyrimidine compounds and their use as PDE10 inhibitors
有权
吡唑并嘧啶化合物及其作为PDE10抑制剂的用途
- Patent Title: Pyrazolopyrimidine compounds and their use as PDE10 inhibitors
- Patent Title (中): 吡唑并嘧啶化合物及其作为PDE10抑制剂的用途
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Application No.: US13579095Application Date: 2011-02-25
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Publication No.: US08969376B2Publication Date: 2015-03-03
- Inventor: Eiji Kawanishi , Mitsuya Hongu , Yoshihito Tanaka
- Applicant: Eiji Kawanishi , Mitsuya Hongu , Yoshihito Tanaka
- Applicant Address: JP Osaka-Shi
- Assignee: Mitsubishi Tanabe Pharma Corporation
- Current Assignee: Mitsubishi Tanabe Pharma Corporation
- Current Assignee Address: JP Osaka-Shi
- Agency: Birch,Stewart, Kolasch & Birch, LLP
- International Application: PCT/JP2011/054997 WO 20110225
- International Announcement: WO2011/105628 WO 20110901
- Main IPC: A61K31/415
- IPC: A61K31/415 ; C07D293/00 ; C07D487/00 ; C07D487/04

Abstract:
The present invention relates to a compound represented by formula [I]: wherein: R1 is hydrogen, halogen, lower alkyl or cyano; Ring A is an optionally substituted heterocyclic group; Ring B is an optionally substituted 3 to 6-membered monocyclic group; and Y is optionally substituted amino, optionally substituted cyclic amino, optionally substituted aliphatic 3 to 6-membered monocyclyloxy, optionally substituted lower alkyl or optionally substituted lower alkyl-O—, or a pharmaceutically acceptable salt thereof, and to their use as PDE10 inhibitor.
Public/Granted literature
- US20120309754A1 PYRAZOLOPYRIMIDINE COMPOUNDS AND THEIR USE AS PDE10 INHIBITORS Public/Granted day:2012-12-06
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