Invention Grant
- Patent Title: Modulators of CFTR
- Patent Title (中): CFTR调制器
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Application No.: US12117941Application Date: 2008-05-09
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Publication No.: US08969386B2Publication Date: 2015-03-03
- Inventor: Sara Hadida-Ruah , Mark Miller , Brian Bear , Jinglan Zhou , Jason McCartney , Peter Grootenhuis
- Applicant: Sara Hadida-Ruah , Mark Miller , Brian Bear , Jinglan Zhou , Jason McCartney , Peter Grootenhuis
- Applicant Address: US MA Boston
- Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee Address: US MA Boston
- Agent Michael J. DiVerdi
- Main IPC: A61K31/44
- IPC: A61K31/44 ; C07D401/00 ; C07D401/04 ; A61K31/444
Abstract:
Compounds of the present invention, and pharmaceutically acceptable compositions thereof, are useful as modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator (“CFTR”). The present invention also relates to methods of treating CFTR mediated diseases using compounds of the present invention.
Public/Granted literature
- US20150031708A1 MODULATORS OF CFTR Public/Granted day:2015-01-29
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