Invention Grant
- Patent Title: Intrathecal baclofen pharmaceutical dosage forms with fewer degradation products
- Patent Title (中): 鞘内巴氯芬药物剂型具有较少的降解产物
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Application No.: US12701342Application Date: 2010-02-05
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Publication No.: US08969414B2Publication Date: 2015-03-03
- Inventor: John J. Foster , Angela S. Strantz
- Applicant: John J. Foster , Angela S. Strantz
- Applicant Address: US MO Hazelwood
- Assignee: Mallinckrodt LLC
- Current Assignee: Mallinckrodt LLC
- Current Assignee Address: US MO Hazelwood
- Main IPC: A61K31/195
- IPC: A61K31/195 ; A61K9/00
Abstract:
The present invention relates generally to a sterile, particulate-free, stable intrathecal baclofen solution with less than 0.5% 4-(4-chlorophenyl)-2-pyrrolidone, a degradation product. These solutions are stable under a variety of storage conditions and for extended periods of time. Also disclosed are methods for preparing such compositions.
Public/Granted literature
- US20100216887A1 INTRATHECAL BACLOFEN PHARMACEUTICAL DOSAGE FORMS WITH FEWER DEGRADATION PRODUCTS Public/Granted day:2010-08-26
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