Invention Grant
US08969514B2 Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
有权
鸟苷酸环化酶的激动剂可用于治疗高胆固醇血症，动脉粥样硬化，冠心病，胆结石，肥胖症和其他心血管疾病
- Patent Title: Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
- Patent Title (中): 鸟苷酸环化酶的激动剂可用于治疗高胆固醇血症，动脉粥样硬化，冠心病，胆结石，肥胖症和其他心血管疾病
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Application No.: US12630654Application Date: 2009-12-03
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Publication No.: US08969514B2Publication Date: 2015-03-03
- Inventor: Kunwar Shailubhai
- Applicant: Kunwar Shailubhai
- Applicant Address: US NY New York
- Assignee: Synergy Pharmaceuticals, Inc.
- Current Assignee: Synergy Pharmaceuticals, Inc.
- Current Assignee Address: US NY New York
- Agent Cynthia Kozakiewicz; Ivor Elrifi
- Main IPC: A61K38/00
- IPC: A61K38/00 ; C07K7/00 ; A61K47/48 ; A61K38/10 ; C07K7/08
Abstract:
This invention also provides a method to prevent, control, and treat a lipid metabolism disorder, a billary disorder, cardiovascular disease, obesity or an endocrine disorder by administering at least one agonist of guanalyte cyclase receptor either alone or in combination with a compound typically used to treat the disorder and or with an inhibitor of cGMP-dependent phosphodieasterases.
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