Invention Grant
US08969524B2 FVIII peptides for immune tolerance induction and immunodiagnostics 有权
FVIII肽用于免疫耐受诱导和免疫诊断

FVIII peptides for immune tolerance induction and immunodiagnostics
Abstract:
The present invention is related to peptides that can be used to reduce the immune response against FVIII or to induce tolerance to human FVIII in patients with, e.g., hemophilia A. Furthermore, the peptides can be used for immunodiagnostic purposes to detect FVIII-specific CD4+ T cells to monitor patients with hemophilia A during replacement therapy and during immune tolerance induction therapy.
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