Invention Grant
- Patent Title: Antibody Fc variants
- Patent Title (中): 抗体Fc变体
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Application No.: US13431489Application Date: 2012-03-27
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Publication No.: US08969526B2Publication Date: 2015-03-03
- Inventor: Monika Baehner , Stefan Jenewein , Manfred Kubbies , Ekkehard Moessner , Tilman Schlothauer
- Applicant: Monika Baehner , Stefan Jenewein , Manfred Kubbies , Ekkehard Moessner , Tilman Schlothauer
- Applicant Address: CH Schlieren
- Assignee: Roche Glycart AG
- Current Assignee: Roche Glycart AG
- Current Assignee Address: CH Schlieren
- Agency: Morrison & Foerster LLP
- Priority: EP11160251 20110329
- Main IPC: C07K16/00
- IPC: C07K16/00 ; A61K39/395 ; A61K39/40 ; C07K1/00
Abstract:
The invention relates to engineered polypeptides comprising Fc variants and their uses. More specifically, Fc variants are described exhibiting reduced effector function. These variants cause a benefit for a patient suffering from a disease which could be treated with an antibody for which it is desirable to reduce the effector function elicited by antibodies.
Public/Granted literature
- US20120251531A1 ANTIBODY Fc VARIANTS Public/Granted day:2012-10-04
Information query
