Invention Grant
- Patent Title: Torque teno virus (TTV) isolates and compositions
- Patent Title (中): 扭转o病毒（TTV）分离物和组合物
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Application No.: US12733355Application Date: 2009-10-16
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Publication No.: US08969536B2Publication Date: 2015-03-03
- Inventor: Gregory Paul Nitzel , Robert Gerard Ankenbauer , Jay Gregory Calvert , Donna Steuerwald Dunyak , Jacqueline Gayle Marx , Nancee Lois Olen , Douglas Steven Pearce , Mira Ivanova Stoeva , James Richard Thompson
- Applicant: Gregory Paul Nitzel , Robert Gerard Ankenbauer , Jay Gregory Calvert , Donna Steuerwald Dunyak , Jacqueline Gayle Marx , Nancee Lois Olen , Douglas Steven Pearce , Mira Ivanova Stoeva , James Richard Thompson
- Applicant Address: US NJ Florham Park
- Assignee: Zoetis LLC
- Current Assignee: Zoetis LLC
- Current Assignee Address: US NJ Florham Park
- Agent Barbara L. Renda; E. Victor Donahue
- International Application: PCT/US2009/005662 WO 20091016
- International Announcement: WO2010/044889 WO 20100422
- Main IPC: C07H21/02
- IPC: C07H21/02 ; C07H21/04 ; C12N15/00 ; C12N1/00 ; C12N7/00 ; C07K14/005 ; C07K16/08 ; A61K39/00
Abstract:
The present invention is directed to novel nucleotide and amino acid sequences of Torque teno virus (“TTV”), including novel genotypes thereof, all of which are useful in the preparation of vaccines for treating and preventing diseases in swine and other animals. Vaccines provided according to the practice of the invention are effective against multiple swine TTV genotypes and isolates. Diagnostic and therapeutic polyclonal and monoclonal antibodies are also a feature of the present invention, as are infectious clones useful in the propagation of the virus and in the preparation of vaccines. Particularly important aspects of the invention include vaccines that provide TTV ORF1 protein, or peptide fragments thereof, as antigen.
Public/Granted literature
- US20110150913A1 TORQUE TENO VIRUS (TTV) ISOLATES AND COMPOSITIONS Public/Granted day:2011-06-23
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