Invention Grant
- Patent Title: Process for the synthesis of cyclic carbamates
- Patent Title (中): 合成环状氨基甲酸酯的方法
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Application No.: US13879221Application Date: 2011-10-14
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Publication No.: US08969550B2Publication Date: 2015-03-03
- Inventor: Meinrad Brenner , Erick M. Carreira , Nicka Chinkov , Miriam Lorenzi , Aleksander Warm , Lothar Zimmermann
- Applicant: Meinrad Brenner , Erick M. Carreira , Nicka Chinkov , Miriam Lorenzi , Aleksander Warm , Lothar Zimmermann
- Applicant Address: CH Visp
- Assignee: Lonza Ltd.
- Current Assignee: Lonza Ltd.
- Current Assignee Address: CH Visp
- Agency: Hoffmann & Baron, LLP
- Priority: EP10013632 20101014
- International Application: PCT/EP2011/005163 WO 20111014
- International Announcement: WO2012/048886 WO 20120419
- Main IPC: C07D265/18
- IPC: C07D265/18

Abstract:
The invention is directed to a process for the preparation of a cyclic carbamate starting with o-aminobenzyl alcohol and/or a suitable salt thereof, which is reacted with a cyclization agent selected from phosgene, diphosgene, triphosgene and mixtures thereof, and in that the reaction carried out in the presence of an aqueous base, and a water-immiscible organic solvent, said organic solvent mainly comprising at least one compound selected from C2-5-alkyl C2-5-carboxylates and mixtures of at least one C2-5-alkyl C2-5-carboxylate with at least one C5-8-alkane.
Public/Granted literature
- US20130211077A1 PROCESS FOR THE SYNTHESIS OF CYCLIC CARBAMATES Public/Granted day:2013-08-15
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