Invention Grant
- Patent Title: PIM kinase inhibitors and preparation methods and use in medicinal manufacture thereof
- Patent Title (中): PIM激酶抑制剂及其药物制备方法及用途
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Application No.: US14177131Application Date: 2014-02-10
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Publication No.: US08969584B2Publication Date: 2015-03-03
- Inventor: Yu Ge
- Applicant: Yu Ge
- Applicant Address: CN Shanghai
- Assignee: Jikai Biosciences, Inc.
- Current Assignee: Jikai Biosciences, Inc.
- Current Assignee Address: CN Shanghai
- Agency: Mei & Mark LLP
- Agent Manni Li
- Priority: CN201110229731 20110811; CN201210271445 20120801
- Main IPC: C07D417/00
- IPC: C07D417/00 ; C07D403/14 ; C07D417/12 ; C07D417/14 ; A61K31/4439 ; A61K31/4545 ; C07D471/08 ; C07D405/14 ; C07D451/02 ; C07D453/02
Abstract:
A Pim kinase inhibitor compound having the structure represented by Formula I, and isomers, diastereomers, enantiomers, tautomers, and pharmaceutically acceptable salts thereof. The compounds significantly inhibit Pim kinase activity and can be used to prepare drugs for treating Pim kinase mediated diseases, such as cancers, autoimmune diseases, allergic reactions, or organ transplant rejection. Also provided are methods for preparing the compounds represented by Formula I.
Public/Granted literature
- US20140162998A1 PIM KINASE INHIBITORS AND PREPARATION METHODS AND USE IN MEDICINAL MANUFACTURE THEREOF Public/Granted day:2014-06-12
Information query
