Systems and methods for generating a CDMA signal s(t) comprising N components involves assigning to each of the N components one unique spreading sequence an selected from a set of M spreading sequences with M≧N, modulating the symbols dn of each component on the assigned unique spreading sequence an, and combining the N symbols dn each being spread with its own unique spreading sequence an to a CDMA signal s(t). The assigned spreading sequences an are selected such that all selected pairs within the set of N spreading sequences are orthogonal or very close to be orthogonal so that cross-correlation components between all spreading sequences an are close to zero or zero.