Invention Grant
US08974541B2 Bone implant comprising a magnesium-containing metallic material with reduced corrosion rate, and methods and kit for producing the bone implant
有权
包括具有降低的腐蚀速率的含镁金属材料的骨植入体,以及用于生产骨植入物的方法和试剂盒
- Patent Title: Bone implant comprising a magnesium-containing metallic material with reduced corrosion rate, and methods and kit for producing the bone implant
- Patent Title (中): 包括具有降低的腐蚀速率的含镁金属材料的骨植入体,以及用于生产骨植入物的方法和试剂盒
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Application No.: US13704346Application Date: 2011-06-15
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Publication No.: US08974541B2Publication Date: 2015-03-10
- Inventor: Berthold Nies , Stefan Glorius
- Applicant: Berthold Nies , Stefan Glorius
- Applicant Address: DE Radebeul
- Assignee: InnoTERE GmbH
- Current Assignee: InnoTERE GmbH
- Current Assignee Address: DE Radebeul
- Agent Gudrun E. Huckett
- Priority: DE102010030135 20100615
- International Application: PCT/EP2011/059954 WO 20110615
- International Announcement: WO2011/157758 WO 20111222
- Main IPC: A61F2/28
- IPC: A61F2/28 ; A61L24/02 ; A61L27/04 ; A61L27/30

Abstract:
The invention relates to a bone implant which comprises a magnesium-containing metallic material having a reduced corrosion rate and inorganic bone cement, and to methods and a kit for producing the bone implant. With a method according to the invention, it is possible to obtain a bone implant which comprises inorganic bone cement and a magnesium-containing metallic material with a corrosion-inhibiting coating which contains magnesium-ammonium phosphates. In the method according to the invention, a magnesium-containing metallic material, of which the surface has a magnesium oxide layer and/or a magnesium salt layer, is combined with inorganic bone cement in order to generate a solid composite material that comprises the inorganic bone cement and the magnesium-containing metallic material. The inorganic bone cement contains inorganic powder constituents, which set in the presence of water to form a solid, and water-soluble phosphate-ion-containing salts, preferably water-soluble phosphate-ion-containing and ammonium-ion-containing salts. According to the invention, the magnesium-containing metallic material is brought into contact with water before and/or during the combination with the inorganic bone cement in the presence of water-soluble ammonium-ion-containing and phosphate-ion-containing salts. Moreover, the inorganic bone cement is set by being brought into contact with water.
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