Invention Grant
US08974785B2 Fully humanized anti-HER2 antibody, preparation method and use thereof
有权
完全人源化的抗HER2抗体，其制备方法和用途
- Patent Title: Fully humanized anti-HER2 antibody, preparation method and use thereof
- Patent Title (中): 完全人源化的抗HER2抗体，其制备方法和用途
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Application No.: US13579180Application Date: 2010-04-16
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Publication No.: US08974785B2Publication Date: 2015-03-10
- Inventor: Chuan Li , Xin Tong , Ying Kan
- Applicant: Chuan Li , Xin Tong , Ying Kan
- Applicant Address: CN Shanghai
- Assignee: Shanghai Biomabs Pharmaceuticals Co., Ltd.
- Current Assignee: Shanghai Biomabs Pharmaceuticals Co., Ltd.
- Current Assignee Address: CN Shanghai
- Agency: Cesari and McKenna, LLP
- Priority: CN201010125241 20100225
- International Application: PCT/CN2010/000511 WO 20100416
- International Announcement: WO2011/103700 WO 20110901
- Main IPC: C07K16/00
- IPC: C07K16/00 ; C07K16/32 ; C07K16/30 ; A61K39/00
Abstract:
The invention provides a fully human anti-HER2 monoclonal antibody, which has an amino acid sequence of heavy chain variable region as shown in SEQ ID NO: 6 and an amino acid sequence of light chain variable region as shown in SEQ ID NO: 8. The invention also discloses the nucleotide sequence encoding the antibody, the expression vector and the host cell comprising the nucleotide sequence, and the use of the antibody for manufacturing the medicament for the treatment of tumor.
Public/Granted literature
- US20120309942A1 FULLY HUMANIZED ANTI-HER2 ANTIBODY, PREPARATION METHOD AND USE THEREOF Public/Granted day:2012-12-06
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