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US08974811B2 Stabilized pharmaceutical formulations comprising antineoplastic compounds 有权
包含抗肿瘤化合物的稳定药物制剂

Stabilized pharmaceutical formulations comprising antineoplastic compounds
Abstract:
The present invention relates to stabilized pharmaceutical formulations prepared from solutions comprising an antineoplastic compound having a cyclic or non-cyclic hydrazine, triazine, or tetrazine group, or a pharmaceutically acceptable salt thereof, and a stabilizer, wherein the stabilizer is an antioxidant and/or more susceptible to nucleophilic attack than the antineoplastic compound.
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