Invention Grant
- Patent Title: Test kit for plasma or serum antibody titer against periodontal disease-causing bacteria
- Patent Title (中): 血浆或血清抗体滴定对牙周病致病细菌的试剂盒
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Application No.: US13994005Application Date: 2011-10-18
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Publication No.: US08975032B2Publication Date: 2015-03-10
- Inventor: Mikio Nozoe
- Applicant: Mikio Nozoe
- Applicant Address: JP Osaka
- Assignee: Sunstar Inc.
- Current Assignee: Sunstar Inc.
- Current Assignee Address: JP Osaka
- Agency: Wenderoth, Lind & Ponack, L.L.P.
- Priority: JP2010-279268 20101215
- International Application: PCT/JP2011/073942 WO 20111018
- International Announcement: WO2012/081306 WO 20120621
- Main IPC: G01N33/68
- IPC: G01N33/68 ; G01N33/569 ; C07K14/195 ; G01N33/543

Abstract:
The object of the present invention is to provide: a test kit for an antibody titer or an antibody against a periodontal disease-causing bacterium in a blood sample, which enables the testing on a periodontal disease in patients having a wide scope of immunotypes with high accuracy and can be treated by an automated device at a high speed; a periodontal disease-causing bacterium antigen protein which can be suitably used in the kit; a method for testing an antibody titer or the presence of an antibody in a blood sample using the kit; and a kit for typing strains of Porphyromonas gingivalis. The present invention discloses: a test kit comprising a set of polypeptides respectively having the acid sequences represented by SEQ ID NOs: 1, 3, 9, 15, 19, 31, 41, 43, 63, 65 and 67; a modified polypeptide having the amino acid sequence represented by SEQ ID NO: 67; and a method for determining an antibody titer or the presence of an antibody against a periodontal disease-causing bacterium in a blood sample separated from a human body, comprising bringing the blood sample into contact with the above-mentioned set of polypeptides.
Public/Granted literature
- US20130316371A1 TEST KIT FOR PLASMA OR SERUM ANTIBODY TITER AGAINST PERIODONTAL DISEASE-CAUSING BACTERIA Public/Granted day:2013-11-28
Information query
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