Invention Grant
- Patent Title: Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors
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Application No.: US13287900Application Date: 2011-11-02
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Publication No.: US08975046B2Publication Date: 2015-03-10
- Inventor: Brian J. Brazeau , Mervyn L. De Souza , Steven J. Gort , Paula M. Hicks , Sherry R. Kollmann , Jose M. Laplaza , Sara C. McFarlan , Fernando A. Sanchez-Riera , Christopher Solheid
- Applicant: Brian J. Brazeau , Mervyn L. De Souza , Steven J. Gort , Paula M. Hicks , Sherry R. Kollmann , Jose M. Laplaza , Sara C. McFarlan , Fernando A. Sanchez-Riera , Christopher Solheid
- Applicant Address: US MN Wayzata
- Assignee: Cargill, Incorporated
- Current Assignee: Cargill, Incorporated
- Current Assignee Address: US MN Wayzata
- Main IPC: C12P17/10
- IPC: C12P17/10 ; C12P13/22 ; C12N9/10 ; C12N9/90
Abstract:
Monatin and certain stereoisomers of monatin, such as R,R monatin and S,R monatin, as well as salts thereof, are produced using polypeptides and biosynthetic pathways. These polypeptides and biosynthetic pathways are also useful in the production of R-2-hydroxy-2-(indoly-3-ylmethyl)-4-keto glutaric acid, an intermediate that is formed in certain monatin synthesis pathways, including some biosynthetic pathways.
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