Invention Grant
US08975230B2 Method of treating ischemic injury with follistatin-like 1 polypeptide
有权
用卵泡抑素样1多肽治疗缺血性损伤的方法
- Patent Title: Method of treating ischemic injury with follistatin-like 1 polypeptide
- Patent Title (中): 用卵泡抑素样1多肽治疗缺血性损伤的方法
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Application No.: US13646204Application Date: 2012-10-05
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Publication No.: US08975230B2Publication Date: 2015-03-10
- Inventor: Kenneth Walsh , Yuichi Oshima , Noriyuki Ouchi
- Applicant: Trustees of Boston University
- Applicant Address: US MA Boston
- Assignee: Trustees of Boston University
- Current Assignee: Trustees of Boston University
- Current Assignee Address: US MA Boston
- Agency: Nixon Peabody LLP
- Agent Ronald J. Eisenstein; Mark J. FitzGerald
- Main IPC: A61P9/10
- IPC: A61P9/10 ; A61P39/06 ; A61K38/17 ; C07K14/545
Abstract:
Described herein are methods and compositions related to the discovery that the Follistatin-like 1 protein (Fstl-1) has metabolic and cardioprotective effects in vivo. Fstl-1 and portions and derivatives or variants thereof can be used to treat or prevent metabolic diseases or disorders and to treat or prevent cardiac damage caused by interrupted cardiac muscle blood supply.
Public/Granted literature
- US20130035282A1 METABOLIC AND CARDIOPROTECTION BY THE MYOKINE FOLLISTATIN-LIKE 1 POLYPEPTIDE Public/Granted day:2013-02-07
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