Invention Grant
- Patent Title: Compositions and methods for treating cancer
- Patent Title (中): 用于治疗癌症的组合物和方法
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Application No.: US14345728Application Date: 2012-09-18
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Publication No.: US08975274B2Publication Date: 2015-03-10
- Inventor: Gordon W. Gribble , Justin M. Lopchuk
- Applicant: Trustees of Dartmouth College
- Applicant Address: US NH Hanover
- Assignee: Trustees of Dartmouth College
- Current Assignee: Trustees of Dartmouth College
- Current Assignee Address: US NH Hanover
- Agency: Licata & Tyrell P.C.
- International Application: PCT/US2012/055847 WO 20120918
- International Announcement: WO2013/043558 WO 20130328
- Main IPC: A61K31/473
- IPC: A61K31/473 ; A61K31/4709 ; C07D401/12 ; C07D219/10 ; C12N5/09

Abstract:
The present invention is bis-acridine or bis-quinoline intercalators having a modified bis(4-aminophenyl)ether tether to improve activity, selectivity, solubility and bioavailability of the antitumor compound.
Public/Granted literature
- US20140228392A1 COMPOSITIONS AND METHODS FOR TREATING CANCER Public/Granted day:2014-08-14
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