Invention Grant
US08975369B2 Protein skeletal module which increases the binding affinity and binding specificity of active polypeptides
有权
增加活性多肽的结合亲和力和结合特异性的蛋白质骨架模块
- Patent Title: Protein skeletal module which increases the binding affinity and binding specificity of active polypeptides
- Patent Title (中): 增加活性多肽的结合亲和力和结合特异性的蛋白质骨架模块
-
Application No.: US14057654Application Date: 2013-10-18
-
Publication No.: US08975369B2Publication Date: 2015-03-10
- Inventor: Kiweon Cha , In-Seop So , Soyoun Kim , Byung-Heon Lee , In San Kim
- Applicant: Kyungpook National University Industry—Academic Cooperation Foundation
- Applicant Address: KR Daegu
- Assignee: Kyungpook National Univrsity Industry-Academic Cooperation Foundation
- Current Assignee: Kyungpook National Univrsity Industry-Academic Cooperation Foundation
- Current Assignee Address: KR Daegu
- Agency: H.C. Park & Associates, PLC
- Priority: KR10-2011-0035613 20110418
- Main IPC: A61K38/00
- IPC: A61K38/00 ; C07K7/00 ; C07K14/485 ; C07K14/705 ; G01N33/68 ; C07K14/47 ; C07K14/54
Abstract:
The present invention relates to a novel protein skeletal module which increases the binding affinity or binding specificity of active polypeptides. More particularly, the present invention relates to a protein skeletal module comprising polypeptides consisting of the 1st to 19th amino acids of the amino acid sequence expressed in sequence number 1; polypeptides comprising active polypeptides; and polypeptides consisting of the 29th to 86th amino acids of the amino acid sequence expressed in sequence number 1. The present invention also relates to a method for preparing the protein skeletal module. The protein skeletal module of the present invention increases the binding affinity or binding specificity of active polypeptides embedded therein, and therefore is effective in diagnosing and treating diseases.
Public/Granted literature
Information query
IPC分类:
