Invention Grant
US08975379B2 Identification of cancer protein biomarkers using proteomic techniques
有权
使用蛋白质组学技术鉴定癌症蛋白质生物标志物
- Patent Title: Identification of cancer protein biomarkers using proteomic techniques
- Patent Title (中): 使用蛋白质组学技术鉴定癌症蛋白质生物标志物
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Application No.: US12644677Application Date: 2009-12-22
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Publication No.: US08975379B2Publication Date: 2015-03-10
- Inventor: Gil G. Mor , David C. Ward , Patricia Bray-Ward
- Applicant: Gil G. Mor , David C. Ward , Patricia Bray-Ward
- Applicant Address: US CT New Haven
- Assignee: Yale University
- Current Assignee: Yale University
- Current Assignee Address: US CT New Haven
- Agency: Wolf, Greenfield & Sacks, P.C.
- Main IPC: C07K16/00
- IPC: C07K16/00 ; C12P21/08 ; C40B40/10 ; A61K39/395 ; G01N33/574 ; C12Q1/68

Abstract:
The claimed invention describes methods to diagnose or aid in the diagnosis of cancer. The claimed methods are based on the identification of biomarkers which are particularly well suited to discriminate between cancer subjects and healthy subjects. These biomarkers were identified using a unique and novel screening method described herein. The biomarkers identified herein can also be used in the prognosis and monitoring of cancer. The invention comprises the use of leptin, prolactin, OPN and IGF-II for diagnosing, prognosis and monitoring of ovarian cancer.
Public/Granted literature
- US20100311047A1 Identification Of Cancer Protein Biomarkers Using Proteomic Techniques Public/Granted day:2010-12-09
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