Invention Grant
- Patent Title: Process for the asymmetric transfer hydrogenation of ketones
- Patent Title (中): 酮的不对称转移氢化方法
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Application No.: US13701580Application Date: 2011-04-14
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Publication No.: US08975396B2Publication Date: 2015-03-10
- Inventor: Richard Wisdom , Joerg Jung , Andreas Meudt
- Applicant: Richard Wisdom , Joerg Jung , Andreas Meudt
- Applicant Address: DE Frankfurt am Main
- Assignee: Euticals GmbH
- Current Assignee: Euticals GmbH
- Current Assignee Address: DE Frankfurt am Main
- Agency: ProPat, L.L.C.
- Priority: EP10004348 20100423
- International Application: PCT/EP2011/001887 WO 20110414
- International Announcement: WO2011/131315 WO 20111027
- Main IPC: C07D223/28
- IPC: C07D223/28
Abstract:
The invention relates to a process for the asymmetric transfer hydrogenation of a ketone substrate to produce as chiral secondary alcohol with an ee of greater than 85% in which an enantio-enriched chiral catalyst containing ruthenium or rhodium is used with a hydrogen donor and in which an anion exchange resin is used as a base.
Public/Granted literature
- US20130123490A1 Process for the asymmetric transfer hydrogenation of ketones Public/Granted day:2013-05-16
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