Certain embodiments of the present invention provide systems and methods for managing medical information. Certain embodiments provide a system for managing medical information. The system includes a data center for centrally storing patient medical data as unstructured encrypted data. The system also includes a patient interface providing storage and retrieval of patient medical data at the data center. The patient interface communicates with the data center to transmit encrypted patient medical data to the data center. The encrypted patient medical data is encrypted at the patient interface using a patient encryption key assigned to a patient. The patient interface is further configured to receive encrypted patient medical data from the data center and decrypt the patient medical data using the patient encryption key assigned to the patient.