A database-driven testing method and system for testing client-server applications are described. The system first receives a command to test a module on a server and identifies in a database a message list corresponding to the module. The message list indicates at least a request message and an expected response message supported by the module to be tested. The system then retrieves from the database a plurality of parameters for the messages in the message list and constructs the request message based on the parameters. The system then transmits the request message to the module on the server, receives a server response message from the server in response to the request message, and compares the server response message with the expected response message.